Creutzfeldt- Jackob Disease: A Case Report with MRI (DWI) Findings.

  • Hari Om Joshi Department of Radiology, Bhaktapur Hospital, Bhaktapur, Nepal
  • Tong Dan Department of Radiology, The First Hospital of Jilin University, Changchun, Jilin, China
  • Ting Ting Yuan Department of Radiology, The First Hospital of Jilin University, Changchun, Jilin, China
  • Ajit Thapa Department of Radiology, TUTH Hospital, Kathmandu, Nepal.
  • Jyotsna Shakya Department of Laboratory Medicine, Manmohan Institute of Health sciences, Kathmandu, Nepal
Keywords: Creutzfeldt-Jakob disease; Transmissible Spongiform Encephalopathy.

Abstract

Transmissible Spongiform Encephalopathy is sub-acute transmissible neurodegenerative disease which affects both human and animals. Among those that affect humans, Creutzfeldt-Jakob disease is the most common. This disease has a genetic basis and characteristic of an infectious disease. Magnetic Resonance Imaging is an important tool in diagnosis of Creutzfeldt-Jakob disease and can assist especially in the early stages of the disease, when the clinical features might not be typical and Electroencephalogram shows normal or nonspecific abnormalities. Newer Magnetic Resonance Imaging techniques such as Diffusion Weighted Imaging have shown to be more sensitive in detecting this disease at its early stage. We report a single case of probable Creutzfeldt-Jakob disease and its peculiar findings on brain magnetic resonance imaging.

Published
2019-08-04